mRNA Vaccines - Researchers Propose A Design Fix

mRNA Vaccines - Researchers Propose A Design Fix An article on University of Cambridge contains this statement, "Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent ‘off-target’ immune responses to enable the safer design of future mRNA therapeutics." If you like this content and want more, I am doing a special lifetime membership offer. Click here: https://www.drbeen.com/yt-special/ Want to support this work?: Buy me a coffee :-) https://www.buymeacoffee.com/DrMobeenSyed Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true PayPal: https://paypal.me/mobeensyed?locale.x=en_US My substack: https://mobeensyedmd.substack.com/ #drbeen #koolbeens #COVID Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. URL list from Friday, Dec. 8 2023 Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses | University of Cambridge https://www.cam.ac.uk/research/news/researchers-redesign-future-mrna-therapeutics-to-prevent-potentially-harmful-immune-responses N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting | Nature https://www.nature.com/articles/s41586-023-06800-3 The Shape and Structure of Proteins - Molecular Biology of the Cell - NCBI Bookshelf https://www.ncbi.nlm.nih.gov/books/NBK26830/#:~:text=A%20protein%20molecule%20is%20made,one%20molecule%20to%20the%20next. Ribosomes, Transcription, Translation | Learn Science at Scitable https://www.nature.com/scitable/topicpage/ribosomes-transcription-and-translation-14120660/#:~:text=Recall%20that%20mRNA%20molecules%20are,protein%20as%20it%20is%20synthesized. Genetic code - Wikipedia https://en.wikipedia.org/wiki/Genetic_code DNA and RNA codon tables - Wikipedia https://en.wikipedia.org/wiki/DNA_and_RNA_codon_tables Pseudouridine - Wikipedia https://en.wikipedia.org/wiki/Pseudouridine Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines | ACS Central Science https://pubs.acs.org/doi/10.1021/acscentsci.1c00197 Ribonucleotide - Wikipedia https://en.wikipedia.org/wiki/Ribonucleotide#:~:text=In%20biochemistry%2C%20a%20ribonucleotide%20is,monomeric%20building%20blocks%20for%20RNA. Translation: DNA to mRNA to Protein | Learn Science at Scitable https://www.nature.com/scitable/topicpage/translation-dna-to-mrna-to-protein-393/#:~:text=The%20process%20of%20translation%20can,transcription%20as%20well%20as%20tRNA.&text=The%20genes%20in%20DNA%20encode,the%20functions%20necessary%20for%20life. Frontiers | On programmed ribosomal frameshifting: the alternative proteomes https://www.frontiersin.org/articles/10.3389/fgene.2012.00242/full#:~:text=Frameshifting%20is%20a%20process%20whereby,downstream%20(%E2%88%921%20frameshift).