Professor Angus Dalgleish, physician, oncologist, pathologist, medical researcher and author. Get your copy of The Death of Science,
https://gazellebookservices.co.uk/pro...
Also by Professor Dalgleish, The Origin of the Virus: The hidden truths behind the microbe that killed millions of people, https://www.amazon.co.uk/dp/185457106...
,physiology,nursing,NCLEX,health,disease,biology,medicine,nurse education,medical education,pathophysiology,campbell,human biology,human body,FD-SriUSpXw,, Health,Society, channel_UCF9IOB2TExg3QIBupFtBDxg, video_FD-SriUSpXw,Biden could give Anthony Fauci ‘preemptive pardon’
This link is to support John's work on Patreon,https://patreon.com/JohnCampbell2?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink
Former head of CDC
https://www.telegraph.co.uk/us/politics/2024/12/05/biden-considers-preemptive-pardons-protect-allies-trump/
Joe Biden’s team
Considering a raft of “preemptive pardons”
Protect his allies from future prosecutions
(Liz Cheney and Adam Schiff)
FBI new lead, Kash Patel
Pardoning allies before any charges are brought,
a highly unusual step???????????????
Example 1, Covid lab accident in China
https://oversight.house.gov/release/final-report-covid-select-concludes-2-year-investigation-issues-500-page-final-report-on-lessons-learned-and-the-path-forward/
COVID-19 ORIGIN: COVID-19 most likely emerged from a laboratory in Wuhan, China.
The FIVE strongest arguments in favor of the “lab leak” theory include:
1. The virus possesses a biological characteristic that is not found in nature.
2. Data shows that all COVID-19 cases stem from a single introduction into humans.
This runs contrary to previous pandemics where there were multiple spillover events.
3. Wuhan is home to China’s foremost SARS research lab, which has a history of conducting gain-of-function research at inadequate biosafety levels.
4. Wuhan Institute of Virology (WIV) researchers were sick with a COVID-like virus in the fall of 2019,
months before COVID-19 was discovered at the wet market.
5. By nearly all measures of science, if there was evidence of a natural origin it would have already surfaced.
PROXIMAL ORIGIN PUBLICATION:
“The Proximal Origin of SARS-CoV-2” publication — which was used repeatedly by public health officials and the media to discredit the lab leak theory
— was prompted by Dr. Fauci to push the preferred narrative that COVID-19 originated in nature.
https://www.nature.com/articles/s41591-020-0820-9
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext
We support the call from the Director-General of WHO to promote scientific evidence and unity over misinformation and conjecture.
Conspiracy theories do nothing but create fear, rumours, and prejudice that jeopardise our global collaboration in the fight against this virus.
The rapid, open, and transparent sharing of data on this outbreak is now being threatened by rumours and misinformation around its origins.
We stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin.
GAIN-OF-FUNCTION RESEARCH:
A lab-related incident involving gain-of-function research is most likely the origin of COVID-19.
Current government mechanisms for overseeing this dangerous gain-of-function research are incomplete, severely convoluted, and lack global applicability.
ECOHEALTH ALLIANCE INC. (ECOHEALTH):
EcoHealth — under the leadership of Dr. Peter Daszak
— used U.S. taxpayer dollars to facilitate dangerous gain-of-function research in Wuhan, China.
After the Select Subcommittee released evidence of EcoHealth violating the terms of its National Institutes of Health (NIH) grant,
the U.S. Department of Health and Human Services (HHS) commenced official debarment proceedings and suspended all funding to EcoHealth.
• New evidence also shows that the Department of Justice (DOJ) has opened an investigation into EcoHealth’s pandemic-era activities.
NIH FAILURES:
NIH’s procedures for funding and overseeing potentially dangerous research are deficient, unreliable, and pose a serious threat to both public health and national security.
Further, NIH fostered an environment that promoted evading federal record keeping laws
Biden pardons son Hunter
Due to be sentenced in two federal cases for gun possession and tax evasion.
Any criminality over a 10-year period
(most expansive order of its kind since Richard Nixon was pardoned in 1974).
,physiology,nursing,NCLEX,health,disease,biology,medicine,nurse education,medical education,pathophysiology,campbell,human biology,human body,P16UnezjVpU,UCF9IOB2TExg3QIBupFtBDxg, Health,Society, channel_UCF9IOB2TExg3QIBupFtBDxg, video_P16UnezjVpU,Concerns
Trust issues, Individual / State
Patient / Doctor
NFR / DNACPR failures
Urgent funding and reform of palliative care,
Need for people to have a real choice.
Could people choose assisted suicide because of fear they will not get the palliative services they need.
Mission creep
Cost of setting up this ‘service’
Will doctors opt out or opt in?
Will juniors be expected to assist seniors administering the ‘service’?
Will there be any career progression implications?
Will the ‘service’ be part of the NHS, carried out in our local hospitals?
Will doctors be forced to refer to the ‘service’
Coercive and controlling behaviour
Vulnerable, poor, unintelligent, demented, those without advocates
How will ‘capacity’ be assessed, which criteria will be used?
Who will assess ‘capacity’
Who will assess psychiatric profile, (any serious illness can cause depression, which is fully reversable)
Who will assess 6 months left to live?
Pressure from relatives
Not wanting to be a burden
Could a ‘right’ to die morph into a ‘duty’ to die.
I am spending my children’s and grandchildren’s inheritance
Any mistakes cannot be undone
Extension to children, mentally ill.
People judged by their worth / usefulness / popularity / wealth / not being cost / not being a burden
Volunteering for death seen as a duty
Freeing up a bed for a young person
Judges interpretation of the law (National and international)
Norm referencing allows for a new norm.
https://www.telegraph.co.uk/news/2024/11/29/result-assisted-dying-bill-vote-commons-silence-mps-ballot/
Tim Farron
“Our society has chosen a dystopian and contagious path if it chooses to facilitate the death of those who have a terminal illness rather than standing with them, weeping with them, valuing them and loving them against the desolation that any of us would feel if we were given a diagnosis of that sort.”
Robert Jenrick
“This Act, if passed, will be subject to activist judges in Strasbourg. They will change it fundamentally and we have to be prepared for that.”
The Commons has voted for assisted dying
– we are not the same country we were yesterday (Tim Stanley)
https://www.telegraph.co.uk/news/2024/11/29/assisted-dying-not-same-country/
https://www.telegraph.co.uk/news/2024/11/29/assisted-dying-not-same-country/
bringing us up to date with Oregon and, I would argue, the Third Reich.
(death could be healthcare, and necessary and kind)
We are not the same country we were; we do not rest on the same moral foundation.
we long stuck to the principle that the state does not take innocent life.
No longer.
State sponsored euthanasia debated in 5 hours
The argument for assisted dying was largely anecdotal,
MPs recounted personal experiences of illness and death, and appeals they had heard from their constituents on assisted dying.
‘unable to take the pain anymore, laid down on a railway line’
Relatives will push the elderly to die early; money will be made; the wedge will thicken;
(terminally ill adults with less than six months to live, two doctors and a judge)
and the British health service being so poor, this will come to be seen as a patriotic or desperate alternative to substandard care.
If you see someone standing on a bridge, thinking about jumping, you don’t just give them a sympathetic smile, do you?
It is the postwar consensus, as social democratic as it is Judeo-
Christian, that is crumbling – giving way to something consumerist and atomising.
,physiology,nursing,NCLEX,health,disease,biology,medicine,nurse education,medical education,pathophysiology,campbell,human biology,human body,Cbja4804sYI,UCF9IOB2TExg3QIBupFtBDxg, Health,Knowledge, channel_UCF9IOB2TExg3QIBupFtBDxg, video_Cbja4804sYI,Scientific discussions with professor Robert Clancy
,physiology,nursing,NCLEX,health,disease,biology,medicine,nurse education,medical education,pathophysiology,campbell,human biology,human body,lqjYmu93sFg,UCF9IOB2TExg3QIBupFtBDxg, Health, channel_UCF9IOB2TExg3QIBupFtBDxg, video_lqjYmu93sFg,Professor Clancy talks about sicnece and his own clinical experience.
,physiology,nursing,NCLEX,health,disease,biology,medicine,nurse education,medical education,pathophysiology,campbell,human biology,human body,5Q5QjEPGNNg,UCF9IOB2TExg3QIBupFtBDxg, Health,Knowledge, channel_UCF9IOB2TExg3QIBupFtBDxg, video_5Q5QjEPGNNg,Fenbendazole Enhancing Anti-Tumor Effect: A Case Series (2021)
https://www.scitechnol.com/peer-review/fenbendazole-enhancing-antitumor-effect-a-case-series-2Kms.php?article_id=14307&fbclid=IwAR0tYpTZb4fp2_AO8e_WGWM5mcqv-RNfI-5SID9OWDcRiwHyHmQBKsjeSKk
Full PDF with radiology
https://www.scitechnol.com/peer-review/fenbendazole-enhancing-antitumor-effect-a-case-series-P3SV.pdf
Background
Fenbendazole (FBZ) is a cheap and readily available anti-parasitic commonly used in veterinary medicine.
FBZ belongs to the benzimidazole drug class which destabilize microtubules through a mechanism similar to the anti-oncogenic vinca alkaloids.
Although there are no reported cases in the literature, there have been several anecdotal stories published on website blogs with individuals praising its ability to treat a wide variety of cancers.
Case Presentations
Three patients with various genitourinary malignancies,
who demonstrated complete response after receiving FBZ therapy,
as a single or supplementary chemotherapeutic agent.
In two patient scenarios, they had experienced progression of metastatic disease despite multiple lines of therapy prior to initiation of FBZ.
No side effects from FBZ were reported.
Conclusion
FBZ appears to be a potentially safe and effective antineoplastic agent,
that can be repurposed for human use in treating genitourinary malignancies.
Further research is necessary to define the role of FBZ as a chemotherapeutic option.
Details
FBZ is a cheap anti-helminthic medication commonly used in veterinary practice,
However, despite multiple anecdotal stories and news outlet reports for its efficacy in treating metastatic cancer,
the clinical literature behind utilizing FBZ as a potential anti-neoplastic agent remains nonexistent.
Case 1
A 63-year-old Caucasian male presented with flank pain, rapid weight loss, and transient fever.
Abdominal Computed Topography (CT) revealed a 3 cm left solid renal mass.
Renal Cell Carcinoma (RCC)
Traditional drugs used then discontinued
One month after discontinuation, repeat MRI showed increase in size of recurrent left renal mass, pancreatic head and body lesion
He also started alternative therapy with FBZ 1 gm three times per week at the suggestion of one of his friends with head/neck cancer.
Interval MRI imaging found near complete resolution of the previously noted left renal mass,
as well as decrease in pancreatic head/body and pelvic bone lesion
Serial imaging for the past 10 months have not shown any evidence of recurrence or metastatic disease.
He has continued taking FBZ without any reported side effects.
Case 2
A 72-year-old caucasian male
Urethral lesion
Distal penectomy
Pathology showing high-grade urothelial carcinoma of the urethra
Four years later, the patient developed a cough,
5.5 cm × 4.0 cm left hilar mass and a left upper lobe nodule, with multiple abnormal lymph nodes
Bronchoscopy with biopsy revealed squamous carcinoma, (probable primary)
Chemotherapy given
Developed progressive retroperitoneal disease
The patient opted for complementary therapy with FBZ 1 gram orally three days per week,
vitamin E 800 mg daily,
curcumin 600 mg daily,
and CBD oil
Serial CTs from the past 9 months showed progressive decrease in size to 0.5 cm × 0.5 cm, complete radiographic response.
Case 3
A 63-year-old Caucasian female
CT imaging revealed a 7.5 cm right lateral bladder mass with extensions
Hydronephrosis requiring percutaneous nephrostomy.
Transurethral Resection of Bladder Tumor (TURBT) demonstrated a large necrotic mass,
pathology confirming urothelial carcinoma with 85% squamous and 2% sarcomatoid histology.
6 cycles over the course of 4 months,
along with concurrent FBZ 1 gram three times weekly.
Follow-up CT revealed no evidence of disease with minimal residual thickening in the right inferior bladder wall
She declined to proceed with cystectomy and remains on surveillance with no evidence of progression.
Discussion
We have three patients with different primary genitourinary tumors who demonstrated complete response after receiving FBZ therapy.
Given evidence of high tolerability and applicability to a wide range of malignancies,
this warrants further investigation for FBZ and other benzimidazoles as safe chemotherapeutic options.
Conclusion
There remains limited data with few published studies on the anti-oncogenic properties of FBZ.
Other benzimidazoles have been studied to a larger extent,
and the knowledge can be drawn upon to help guide future FBZ studies,
and to gauge the efficacy of this drug class whether as a solitary agent or in combination therapy.
Given the potential benefits of FBZ with what seems to be a limited toxicity profile,
further research is warranted to evaluate the clinical settings in which this medication may be beneficial and repurposed,
for patients with progressive genitourinary malignancy and possibly in other malignant settings as well.
,1,Professor Angus Dalgleish, physician, oncologist, pathologist, medical researcher and author. Get your copy of The Death of Science,
https://gazellebookservices.co.uk/pro...
Also by Professor Dalgleish, The Origin of the Virus: The hidden truths behind the microbe that killed millions of people, https://www.amazon.co.uk/dp/185457106...
